🧪Clinical Trials · September 2026
Every clinical trial among this month's papers (2026.09.01 → 2026.09.26), as PubMed types them, with what their MeSH terms say they study.
- Trials
- 283 224 randomized
- Phase 3
- 44 16%
- Phase 2
- 39 14%
- Phase 1
- 27 10%
- Phase not stated
- 173 61%
Trial readouts
Scored and written by gpt-4o-mini from this month's trials; each sentence checked against its abstract.
- Phase 3 Endpoint met
Aumolertinib combined with radiotherapy significantly improved progression-free survival in EGFR-mutated stage III NSCLC patients.
- Phase 3 Endpoint met
Self-acupressure significantly improved fatigue, sleep disturbance, and depression in breast cancer survivors.
- Phase 3 Endpoint met
Blinatumomab showed a significant improvement in event-free survival compared to chemotherapy in pediatric ALL patients.
- Phase 3 Endpoint met
Durvalumab plus FLOT improved overall survival in patients with resectable gastric adenocarcinoma in a phase 3 trial.
- Phase 3 Endpoint met
Oveporexton significantly improves mean sleep latency in narcolepsy type 1 patients.
- Phase not stated Endpoint met
PCSK9 inhibitor therapy significantly reduced intracranial artery stenosis compared to high-intensity statin alone.
- Phase not stated Endpoint not stated
The SASSY study compares single-anastomosis sleeve ileal bypass to sleeve gastrectomy for severe obesity.
- Phase not stated Endpoint met
The combination of TCM and HIFU significantly reduced pain and uterine volume in adenomyosis patients.
By disease area
MeSH disease categories of each trial's disease terms, as a share of all 283 trials. A trial can fall in several, so the shares add up to more than 100%; 44 have none. Beside each, its share in each whole month Mar–Aug (202–311 trials a month): the average, and the range it moved in. ▲ or ▼ marks this month above or below that range, for areas with 10 or more trials this month.
- Phase 3
- Phase 2
- Phase 1
- Not stated
Show table
| Disease area | Phase 3 | Phase 2 | Phase 1 | Not stated | Trials | Share | Mar–Aug avg | Range |
|---|---|---|---|---|---|---|---|---|
| Neoplasms | 28 | 29 | 18 | 32 | 107 | 38% | 34% | 26–41% |
| Immune System Diseases | 6 | 8 | 12 | 17 | 43 | 15% | 14% | 11–15% |
| Nervous System Diseases | 2 | 4 | 1 | 31 | 38 | 13% | 15% | 9–19% |
| Cardiovascular Diseases | 1 | 0 | 6 | 30 | 37 | 13% | 11% | 10–13% |
| Endocrine System Diseases | 1 | 1 | 3 | 29 | 34 | 12% | 12% | 9–15% |
| Hemic and Lymphatic Diseases | 10 | 10 | 8 | 4 | 32 | 11% | 8% | 6–9% |
| Nutritional and Metabolic Diseases | 4 | 0 | 0 | 28 | 32 | 11% | 13% | 10–18% |
| Digestive System Diseases | 8 | 7 | 1 | 15 | 31 | 11% | 8% | 7–10% |
| Urogenital Diseases | 4 | 1 | 5 | 19 | 29 | 10% | 11% | 9–14% |
| Respiratory Tract Diseases | 9 | 3 | 3 | 7 | 22 | 8% | 12% | 8–15% |
| Infections | 4 | 1 | 3 | 12 | 20 | 7% | 8% | 5–12% |
| Skin and Connective Tissue Diseases | 4 | 3 | 1 | 12 | 20 | 7% | 9% | 6–10% |
| Mental Disorders | 2 | 2 | 0 | 9 | 13 | 5% | 4% | 2–6% |
| Congenital, Hereditary, and Neonatal Diseases and Abnormalities | 5 | 2 | 0 | 5 | 12 | 4% | 3% | 3–4% |
| Stomatognathic Diseases | 0 | 3 | 0 | 7 | 10 | 4% | 2% | 1–3% |
| Musculoskeletal Diseases | 1 | 1 | 0 | 6 | 8 | 3% | 4% | 2–6% |
| Eye Diseases | 0 | 1 | 1 | 3 | 5 | 2% | 2% | 0–3% |
| Otorhinolaryngologic Diseases | 0 | 1 | 0 | 2 | 3 | 1% | 2% | 1–2% |
| Wounds and Injuries | 1 | 0 | 0 | 2 | 3 | 1% | 2% | 1–4% |
| Chemically-Induced Disorders | 0 | 0 | 0 | 2 | 2 | 1% | 1% | 1–2% |
283 of 283 trials
- Oveporexton for Narcolepsy Type 1 - Results from Two Phase 3 Trials. ↗
- Disease
- Narcolepsy
- Substances
- Orexin Receptors · Triazoles
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Serotype-specific Immunity and Association With Pneumococcal Carriage Following 3+1, 3+0, and 2+1 Schedules of 10-valent Pneumococcal Conjugate Vaccine. ↗
- Disease
- Pneumococcal Infections
- Substances
- Pneumococcal Vaccines · Antibodies, Bacterial · Immunoglobulin G
- Therapy
- Immunization Schedule
- Three-Year Follow-up of the Randomized Trial Comparing Open Versus Laparoscopic Surgery for Primary Tumor Resection in Patients With Noncurable Stage IV Colon Cancer (JCOG1107). ↗
- Disease
- Colonic Neoplasms · Adenocarcinoma · Carcinoma, Adenosquamous
- Substances
- Bevacizumab · Oxaliplatin · Capecitabine
- Therapy
- Laparoscopy · Colectomy
- Research area
- Postoperative Outcomes in Robotic Surgery
- Phase III trial of sodium dichloroacetate for pyruvate dehydrogenase complex deficiency in children. ↗
- Disease
- Pyruvate Dehydrogenase Complex Deficiency Disease
- Substances
- Dichloroacetic Acid · Glutathione Transferase · Lactic Acid
- Health-related quality of life with adjuvant immune checkpoint inhibition in renal cell carcinoma: A qualitative study of UK participants in the phase III RAMPART trial. ↗
- Disease
- Carcinoma, Renal Cell · Kidney Neoplasms
- Substances
- Immune Checkpoint Inhibitors
- Research area
- Survival Outcomes in Cancer Therapy
- RENOIR phase 3 rituximab-lenalidomide vs rituximab as maintenance treatment in relapsed/refractory follicular lymphoma. ↗
- Disease
- Lymphoma, Follicular
- Substances
- Rituximab · Lenalidomide
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Maintenance Chemotherapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Induction and concurrent aumolertinib with radiotherapy for EGFR-mutated stage III NSCLC: results of phase III ADVANCE trial and real-world validation. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- ErbB Receptors
- Research area
- Survival Outcomes in Cancer Therapy
- Perioperative durvalumab plus fluorouracil, leucovorin, oxaliplatin, and docetaxel for resectable gastric and gastro-oesophageal junction adenocarcinoma (MATTERHORN): final results of overall survival and event-free survival by pathological response in a global, randomised, double-blind, placebo-controlled, multicentre, phase 3 trial. ↗
- Disease
- Adenocarcinoma · Esophageal Neoplasms · Stomach Neoplasms
- Substances
- Antibodies, Monoclonal · Docetaxel · Fluorouracil
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- AAML1831: A Phase III Trial Comparing Standard Induction Therapy With CPX-351 in De Novo Pediatric AML: A Report From the Children's Oncology Group. ↗
- Disease
- Leukemia, Myeloid, Acute
- Substances
- Daunorubicin · Cytarabine · Gemtuzumab
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Induction Chemotherapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Long-Term Follow-Up of JCOG1008, a Randomized Phase II/III Trial of Chemoradiotherapy Comparing 3-Weekly Cisplatin With Weekly Cisplatin in Postoperative Head and Neck Cancer. ↗
- Disease
- Head and Neck Neoplasms · Squamous Cell Carcinoma of Head and Neck
- Substances
- Cisplatin · Antineoplastic Agents
- Therapy
- Chemoradiotherapy · Drug Administration Schedule
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Effects of self-acupressure on the fatigue-sleep disturbance-depression symptom cluster in breast cancer survivors: a phase III randomised controlled trial. ↗
- Disease
- Breast Neoplasms
- Therapy
- Self Care
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Blinatumomab for Replacing Chemotherapy in Pediatric Acute Lymphoblastic Leukemia. ↗
- Disease
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma · Precursor Cell Lymphoblastic Leukemia-Lymphoma · Infections
- Substances
- Antibodies, Bispecific · Antineoplastic Agents
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Consolidation Chemotherapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- High-Dose Intravenous Vitamin C and Mortality and Organ Dysfunction in Severe Burn Injury: The VICTORY Randomized Clinical Trial. ↗
- Disease
- Burns
- Substances
- Ascorbic Acid · Cardiotonic Agents · Vasoconstrictor Agents
- Therapy
- Administration, Intravenous · Renal Replacement Therapy
- Adjuvant oxaliplatin with S-1 (SOX) versus S-1 for stage II-III gastric cancer (CAPITAL): A randomized, open-label, phase 3 trial. ↗
- Disease
- Stomach Neoplasms · Adenocarcinoma
- Substances
- Oxaliplatin · Tegafur · Oxonic Acid
- Therapy
- Chemotherapy, Adjuvant · Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Improved quality of life and prolonged survival with add-on homeopathic treatment in patients with non-small cell lung cancer: a prospective, randomized, placebo-controlled, double-blind, three-arm, multicenter study. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Materia Medica
- Therapy
- Homeopathy
- Magrolimab Plus Azacitidine Versus Placebo Plus Azacitidine in Patients With Untreated Higher-Risk Myelodysplastic Syndromes: The Phase III ENHANCE Study. ↗
- Disease
- Myelodysplastic Syndromes
- Substances
- Azacitidine · Antibodies, Monoclonal, Humanized
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Obinutuzumab or Tacrolimus in Primary Membranous Nephropathy. ↗
- Disease
- Glomerulonephritis, Membranous · Infections · Neutropenia
- Substances
- Antibodies, Monoclonal, Humanized · Immunosuppressive Agents · Tacrolimus
- Therapy
- Administration, Oral · Remission Induction
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- primary analysis of the RANDOMIZED eortc-2139/columbus-ad trial: Adjuvant encorafenib and binimetinib versus placebo in high-risk stage II BRAF-V600E/K melanoma. ↗
- Disease
- Melanoma · Skin Neoplasms
- Substances
- Benzimidazoles · Carbamates · Proto-Oncogene Proteins B-raf
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Chemotherapy, Adjuvant
- Research area
- Survival Outcomes in Cancer Therapy
- Assessing time to symptomatic progression, a patient-relevant efficacy endpoint, in the MARIPOSA study in non-small cell lung cancer. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Indoles · Pyrimidines · Aniline Compounds
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Concizumab in patients with hemophilia A or B without inhibitors: 56-week cutoff results of the phase 3 explorer8 study. ↗
- Disease
- Hemophilia A · Hemophilia B
- Substances
- Antibodies, Monoclonal, Humanized
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Phase 3 Trial of Oral Infigratinib in Children with Achondroplasia. ↗
- Disease
- Achondroplasia
- Substances
- Pyrimidines · Receptor, Fibroblast Growth Factor, Type 3 · Phenylurea Compounds
- Therapy
- Administration, Oral · Drug Administration Schedule
- Weight and metabolic changes in patients with schizophrenia treated with paliperidone palmitate 6-month formulation versus paliperidone palmitate 3-month formulation: a post-hoc analysis. ↗
- Disease
- Schizophrenia
- Substances
- Paliperidone Palmitate · Antipsychotic Agents · Delayed-Action Preparations
- Therapy
- Delayed-Action Preparations
- Efficacy, Safety, and Pharmacokinetics of Upadacitinib Among Patients in East Asia With Moderately to Severely Active Ulcerative Colitis: A Post Hoc Subanalysis of Randomized Phase 3 Studies. ↗
- Disease
- Colitis, Ulcerative
- Substances
- Heterocyclic Compounds, 3-Ring · Janus Kinase 1 · Janus Kinase Inhibitors
- Therapy
- Remission Induction
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Remibrutinib impact on disease control, sleep, and quality of life: Analysis of phase 3 REMIX-1/2. ↗
- Substances
- Pyrimidines · Protein Kinase Inhibitors · Agammaglobulinaemia Tyrosine Kinase
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Efficacy and safety of ferric citrate tablets in Chinese patients with hyperphosphatemia undergoing maintenance hemodialysis: a multicenter, randomized, open-label, active-controlled, phase III trial. ↗
- Disease
- Hyperphosphatemia
- Substances
- Ferric Compounds · Sevelamer · Phosphorus
- Therapy
- Renal Dialysis
- First-line anlotinib versus bevacizumab plus CapeOX in RAS/BRAF wild-type unresectable metastatic colorectal cancer (ANCHOR): a multicenter, prospective, randomized, phase 3 trial. ↗
- Disease
- Colorectal Neoplasms
- Substances
- Bevacizumab · Capecitabine · Quinolines
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa. ↗
- Disease
- Glycogen Storage Disease Type I
- Substances
- Gene Therapy Agents · Glucose-6-Phosphatase · Starch
- Therapy
- Genetic Therapy
- Manual, digital, and AI tumour-infiltrating lymphocyte scoring: a secondary analysis of the APHINITY randomised trial. ↗
- Disease
- Breast Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized · Trastuzumab
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- High-dose radiotherapy in patients with high-risk prostate cancers treated with long-term androgen deprivation therapy (GETUG AFU 18): a randomised, phase 3 trial. ↗
- Disease
- Prostatic Neoplasms
- Substances
- Androgen Antagonists
- Therapy
- Radiotherapy Dosage
- Adjuvant alectinib versus chemotherapy in resected ALK-positive non-small-cell lung cancer (ALINA): health-related quality-of-life and safety outcomes from a randomised, open-label, phase 3 trial. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Piperidines · Carbazoles · Anaplastic Lymphoma Kinase
- Therapy
- Chemotherapy, Adjuvant · Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Ivonescimab plus chemotherapy versus placebo plus chemotherapy in patients with advanced EGFR-mutated non-small-cell lung cancer after disease progression on EGFR tyrosine kinase inhibitor therapy (HARMONi): a multicentre, randomised, double-blind, phase 3 trial. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- ErbB Receptors · Protein Kinase Inhibitors · Pemetrexed
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Durvalumab and tremelimumab, with or without lenvatinib, combined with transarterial chemoembolisation in participants with embolisation-eligible hepatocellular carcinoma (EMERALD-3): a global, randomised, open-label, sponsor-blinded, phase 3 study. ↗
- Disease
- Carcinoma, Hepatocellular · Liver Neoplasms
- Substances
- Phenylurea Compounds · Antibodies, Monoclonal, Humanized · Quinolines
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Chemoembolization, Therapeutic
- Research area
- Survival Outcomes in Cancer Therapy
- Ovarian reserve as a measure of adjuvant chemotherapy benefit in hormone receptor positive (HR-positive), HER2-negative, node-positive breast cancer in SWOG S1007 (RxPONDER). ↗
- Disease
- Breast Neoplasms
- Substances
- Anti-Mullerian Hormone · Receptors, Estrogen · Follicle Stimulating Hormone
- Therapy
- Chemotherapy, Adjuvant · Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Duration and characteristics of hypoglycemia with once-weekly insulin efsitora alfa versus once-daily basal insulins in adults with type 2 diabetes: Exploratory safety analysis of QWINT 2-4. ↗
- Disease
- Diabetes Mellitus, Type 2 · Hypoglycemia
- Substances
- Hypoglycemic Agents · Insulin · Blood Glucose
- Therapy
- Drug Administration Schedule
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Matching-adjusted indirect comparison of fruquintinib versus ramucirumab in advanced gastric or gastroesophageal junction adenocarcinoma. ↗
- Disease
- Adenocarcinoma · Stomach Neoplasms · Esophageal Neoplasms
- Substances
- Ramucirumab · Antibodies, Monoclonal, Humanized · Quinazolines
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- SKYSCRAPER-01: Tiragolumab in Combination With Atezolizumab in Previously Untreated PD-L1-High, Locally Advanced, Unresectable or Metastatic Non-Small Cell Lung Cancer. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized · B7-H1 Antigen
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Lorlatinib versus crizotinib as first-line treatment for advanced ALK-positive non-small-cell lung cancer: 7-year update from the phase III CROWN study. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Crizotinib · Lactams · Lactams, Macrocyclic
- Switching to Daily Doravirine/Islatravir (100/0.25 mg) Maintains Viral Suppression Through Week 48 Despite Baseline Non-Nucleoside Reverse Transcriptase Inhibitor Resistance-Associated Mutations or M184I/V in Proviral DNA. ↗
- Disease
- HIV Infections
- Substances
- Triazoles · DNA, Viral · Pyridones
- First-line ibrutinib plus venetoclax for nonblastoid mantle cell lymphoma in patients ≥65 years old or with TP53 mutations. ↗
- Disease
- Lymphoma, Mantle-Cell
- Substances
- Piperidines · Sulfonamides · Bridged Bicyclo Compounds, Heterocyclic
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Exa-cel in Children with Transfusion-Dependent β-Thalassemia or Sickle Cell Disease. ↗
- Disease
- Anemia, Sickle Cell · beta-Thalassemia · Vaso-Occlusive Crises
- Substances
- Fetal Hemoglobin · Repressor Proteins · Gene Therapy Agents
- Therapy
- Erythrocyte Transfusion · Genetic Therapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Osimertinib With or Without Chemotherapy in Advanced Non-Small Cell Lung Cancer With EGFR and Concurrent TP53 Mutations: A Randomized Clinical Trial. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Acrylamides · Aniline Compounds · Carboplatin
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Validation of the lung immune prognostic index in extensive-stage small cell lung cancer: Post hoc analysis of the caspian and IMpower133 phase 3 trials. ↗
- Disease
- Lung Neoplasms · Small Cell Lung Carcinoma
- Therapy
- Immunotherapy · Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- EuroNet-PHL-LP1: complete resection or low-dose chemotherapy for pediatric low-risk nodular lymphocyte-predominant Hodgkin lymphoma. ↗
- Disease
- Hodgkin Disease
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Addition of High-Dose Vitamin D3 to Standard Treatment in Patients With Metastatic Colorectal Cancer: The SOLARIS Randomized Clinical Trial (Alliance A021703). ↗
- Disease
- Colorectal Neoplasms · Neutropenia · Hypertension
- Substances
- Bevacizumab · Camptothecin · Cholecalciferol
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- A phase 2 pharmacokinetic and pharmacodynamic dose-finding study of oral NEPA for chemotherapy-induced nausea and vomiting in pediatric patients with cancer. ↗
- Disease
- Neoplasms
- Substances
- Palonosetron · Antineoplastic Agents · Quinuclidines
- Therapy
- Administration, Oral
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Ceperognastat in Early Symptomatic Alzheimer Disease: A Randomized Clinical Trial. ↗
- Disease
- Alzheimer Disease
- Substances
- tau Proteins · Acetylglucosaminidase · Enzyme Inhibitors
- Therapy
- Administration, Oral
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Use of the bacterial lysate OM-85 for the primary prevention of wheezing lower respiratory illness in preschool children: a randomised, placebo-controlled trial. ↗
- Disease
- Asthma · Respiratory Tract Infections
- Substances
- Bacterial Lysates
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Molecular evaluation of residual disease following neoadjuvant chemotherapy in triple-negative breast cancer CALGB 40603 (Alliance). ↗
- Disease
- Triple Negative Breast Neoplasms
- Substances
- Immunoconjugates
- Therapy
- Neoadjuvant Therapy
- A Randomized Phase II Study of Combination Atezolizumab and Varlilumab (CDX-1127) with or without Cobimetinib in Previously Treated Unresectable Biliary Tract Cancer. ↗
- Disease
- Biliary Tract Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized · Piperidines · Azetidines
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- A Phase II Feasibility Study Combining Pembrolizumab and Metformin in Patients with Metastatic Head and Neck Cancer. ↗
- Disease
- Head and Neck Neoplasms · Squamous Cell Carcinoma of Head and Neck
- Substances
- Metformin · Antibodies, Monoclonal, Humanized
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Biomarker Analysis from Patients with Metastatic PDAC Treated with TGFβ Antibody NIS793 plus Abraxane + Gemcitabine versus Abraxane + Gemcitabine Alone in a Phase II, Open-Label, Randomized Study. ↗
- Disease
- Carcinoma, Pancreatic Ductal · Pancreatic Neoplasms
- Substances
- Gemcitabine · Deoxycytidine · Transforming Growth Factor beta
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- A multicenter randomized phase II/III trial of salvage treatment for refractory primary central nervous system lymphoma using tirabrutinib: JCOG2314 (ReSTART). ↗
- Disease
- Central Nervous System Neoplasms · Lymphoma
- Substances
- Pyrimidines · Protein Kinase Inhibitors
- Therapy
- Salvage Therapy · Cranial Irradiation
- Intismeran Autogene Plus Pembrolizumab Versus Pembrolizumab Alone in High-Risk Resected Melanoma: 5-Year Update of the Randomized Phase IIb KEYNOTE-942 Study. ↗
- Disease
- Melanoma · Skin Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized · Antineoplastic Agents, Immunological
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Azacitidine-Venetoclax or Induction Chemotherapy for Acute Myeloid Leukemia. ↗
- Disease
- Leukemia, Myeloid, Acute
- Substances
- Azacitidine · Bridged Bicyclo Compounds, Heterocyclic · Nucleophosmin
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Induction Chemotherapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Long-term outcomes after a randomized phase II trial of nerve growth factor eye drops for optic pathway gliomas: four-year follow-up findings in children. ↗
- Disease
- Optic Nerve Glioma
- Substances
- Nerve Growth Factor · Ophthalmic Solutions
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- PDE10A Inhibition in Schizophrenia: A Randomised, Placebo-Controlled Phase 2 Study of Alofropodect (CPL'36) in Patients Experiencing Acute Schizophrenia. ↗
- Disease
- Schizophrenia
- Substances
- Antipsychotic Agents · Phosphoric Diester Hydrolases · Phosphodiesterase Inhibitors
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Oral GLP-1RA TERN-601 for Adults With Obesity/Overweight: Placebo-Controlled, Multiple-Ascending-Dose, Phase 1 and 2 Studies. ↗
- Substances
- Glucagon-Like Peptide-1 Receptor Agonists · Glucagon-Like Peptide-1 Receptor
- Therapy
- Administration, Oral
- Research area
- Obesity and Metabolic Disorders
- Five-year follow-up of OPTIC: long-term efficacy, safety, and mutation analyses of ponatinib in chronic-phase chronic myeloid leukemia from a randomized phase 2 trial. ↗
- Substances
- Pyridazines · Imidazoles · Fusion Proteins, bcr-abl
- Efficacy and safety of duvakitug in patients with ulcerative colitis (RELIEVE UCCD): a phase 2b, randomised, placebo-controlled trial. ↗
- Disease
- Colitis, Ulcerative
- Substances
- Antibodies, Monoclonal · Antibodies, Monoclonal, Humanized
- Therapy
- Remission Induction
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Efficacy and safety of duvakitug in patients with Crohn's disease (RELIEVE UCCD): a phase 2b, randomised, placebo-controlled trial. ↗
- Disease
- Crohn Disease
- Substances
- Antibodies, Monoclonal, Humanized · Antibodies, Monoclonal
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Results of intensifying radiation treatment in advanced laryngeal, hypopharyngeal (LH) and oropharyngeal cancers (OPC) using metabolic dose escalation strategies: (INTELHOPE). ↗
- Disease
- Oropharyngeal Neoplasms · Hypopharyngeal Neoplasms · Laryngeal Neoplasms
- Substances
- Fluorodeoxyglucose F18 · Cisplatin · Radiopharmaceuticals
- Therapy
- Radiotherapy Dosage · Chemoradiotherapy
- Population pharmacokinetic analysis of pirtobrutinib, a non-covalent BTK inhibitor, in patients with hematological malignancies from the Phase 1/2 BRUIN study. ↗
- Disease
- Hematologic Neoplasms
- Substances
- Protein Kinase Inhibitors · Agammaglobulinaemia Tyrosine Kinase · Pyrimidines
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Venetoclax plus pediatric regimen in adolescents and adults with Ph-negative acute lymphoblastic leukemia. ↗
- Disease
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Substances
- Bridged Bicyclo Compounds, Heterocyclic · Sulfonamides
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Remission Induction
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Ivonescimab plus chemotherapy as first-line treatment for advanced thymic carcinoma: preliminary results of a phase II trial with biomarker analyses. ↗
- Disease
- Thymus Neoplasms · Thymoma
- Substances
- Antibodies, Bispecific · Paclitaxel · Carboplatin
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Etuvetidigene Autotemcel for the Treatment of Wiskott-Aldrich Syndrome. ↗
- Disease
- Wiskott-Aldrich Syndrome
- Substances
- Gene Therapy Agents · Wiskott-Aldrich Syndrome Protein
- Therapy
- Genetic Therapy · Hematopoietic Stem Cell Transplantation
- Selinexor combined with R-CHOP achieved a high response rate in newly diagnosed double/triple-hit lymphoma. ↗
- Substances
- Vincristine · Prednisone · Cyclophosphamide
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Biomarker-Stratified Phase II Trial of Trastuzumab Rezetecan in Advanced Salivary Gland Carcinoma Across Cohorts With High and Low Human Epidermal Growth Factor Receptor 2 Expression. ↗
- Disease
- Salivary Gland Neoplasms
- Substances
- Trastuzumab · Antibodies, Monoclonal, Humanized · Immunoconjugates
- Research area
- Survival Outcomes in Cancer Therapy
- Darolutamide Alone and in Combination With Goserelin in Androgen Receptor-Positive Salivary Gland Carcinoma: Results From the Phase II DISCOVARY Trial. ↗
- Disease
- Salivary Gland Neoplasms
- Substances
- Goserelin · Receptors, Androgen
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Efficacy, safety and circulating tumor cell dynamics in patients treated with Eribulin for HER2-negative advanced breast cancer - results from the phase II DETECT IVb trial. ↗
- Disease
- Breast Neoplasms
- Substances
- Polyether Polyketides · Ketones · Furans
- Research area
- Survival Outcomes in Cancer Therapy
- Induction FLOT Chemotherapy Prior to Neoadjuvant Chemoradiotherapy in the Treatment of Lower Esophageal and Proximal Gastric Adenocarcinoma: A Phase II, Single-Arm Clinical Trial. ↗
- Disease
- Stomach Neoplasms · Adenocarcinoma · Esophageal Neoplasms
- Substances
- Paclitaxel · Carboplatin
- Therapy
- Neoadjuvant Therapy · Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Camrelizumab, Apatinib, and Radiotherapy in Locally Advanced, Unresectable Hepatocellular Carcinoma: A Phase II Study. ↗
- Disease
- Carcinoma, Hepatocellular · Liver Neoplasms
- Substances
- Pyridines · Antibodies, Monoclonal, Humanized
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Chemoradiotherapy
- Research area
- Survival Outcomes in Cancer Therapy
- Neoadjuvant chemoimmunotherapy with afatinib for locally advanced head and neck squamous cell carcinoma (neoCHANCE-2): an open-label, single-arm, phase 2 study. ↗
- Disease
- Squamous Cell Carcinoma of Head and Neck · Head and Neck Neoplasms
- Substances
- Afatinib
- Therapy
- Neoadjuvant Therapy · Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Camrelizumab plus nimotuzumab as second-line therapy for advanced esophageal squamous cell carcinoma: a multicenter phase II study. ↗
- Disease
- Esophageal Squamous Cell Carcinoma · Esophageal Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Long-term outcomes of azacitidine, venetoclax, and gilteritinib in newly diagnosed FLT3-mutated AML. ↗
- Disease
- Leukemia, Myeloid, Acute
- Substances
- fms-Like Tyrosine Kinase 3 · Bridged Bicyclo Compounds, Heterocyclic · Pyrazines
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Baricitinib for refractory chronic graft-versus-host disease: results of a phase 1/2 study. ↗
- Disease
- Graft vs Host Disease
- Substances
- Purines · Pyrazoles · Sulfonamides
- Therapy
- Hematopoietic Stem Cell Transplantation
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Safety and efficacy of allogeneic CD19-directed CAR-T therapy CTX110 in relapsed/refractory B-cell non-Hodgkin lymphoma. ↗
- Disease
- Lymphoma, B-Cell
- Substances
- Receptors, Chimeric Antigen
- Therapy
- Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- A phase II multi-institutional single arm trial evaluating TG4010 vaccine plus nivolumab in non-small cell lung cancer. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Cancer Vaccines · Nivolumab · Immune Checkpoint Inhibitors
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- CD19 CAR T-cell therapy (GLPG5101) for relapsed or refractory B-cell non-Hodgkin lymphoma (ATALANTA-1): phase 1 results from a single-arm, multicentre, phase 1/2 study. ↗
- Disease
- Lymphoma, B-Cell
- Substances
- Receptors, Chimeric Antigen
- Therapy
- Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Epcoritamab with rituximab and lenalidomide as first-line treatment for follicular lymphoma (EPCORE NHL-2): an open-label, multicentre, phase 1/2 b trial. ↗
- Disease
- Lymphoma, Follicular
- Substances
- Lenalidomide · Rituximab
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Vimseltinib for patients with tenosynovial giant cell tumor: A multicenter, open-label, phase 2 trial. ↗
- Disease
- Giant Cell Tumor of Tendon Sheath
- Substances
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor · Protein Kinase Inhibitors · Pyridines
- Population Pharmacokinetics and Exposure-Response Analyses of Savolitinib Alone or in Combination With Osimertinib in Patients With Locally Advanced or Metastatic Solid Tumors. ↗
- Disease
- Neoplasms
- Substances
- Indoles · Pyrimidines · Aniline Compounds
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Efficacy and Safety of Camrelizumab Combined with Concurrent Chemoradiotherapy in Locally Advanced Cervical Cancer: A Phase II Single-Arm Clinical Trial. ↗
- Disease
- Uterine Cervical Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized
- Therapy
- Chemoradiotherapy
- Research area
- Survival Outcomes in Cancer Therapy
- Long-Term Hematologic Effects of Selumetinib Treatment in Children With Neurofibromatosis Type 1-Associated Plexiform Neurofibromas. ↗
- Disease
- Neurofibroma, Plexiform · Neurofibromatosis 1
- Substances
- Benzimidazoles · Protein Kinase Inhibitors
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Safety and Immunogenicity of a PD-1-Enhanced HIV-1 Therapeutic DNA Vaccine: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Clinical Trial in People With HIV-1 on Antiretroviral Therapy. ↗
- Disease
- HIV Infections
- Substances
- Vaccines, DNA · AIDS Vaccines
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Safety, Pharmacokinetics, and Pharmacodynamics of Single-Dose Programmed Cell Death Protein 1 Inhibitor, Budigalimab, in People With HIV-1 With Antiretroviral Therapy-Suppressed Viral Load. ↗
- Disease
- HIV Infections
- Substances
- Antibodies, Monoclonal · Antibodies, Monoclonal, Humanized · Anti-HIV Agents
- Research area
- Psychosocial Impact of Cancer and HIV
- Dose Selection for Ceftibuten Combined with Avibactam Tomilopil, a Potential Oral Alternative to Carbapenems for Patients with Complicated Urinary Tract Infections. ↗
- Disease
- Urinary Tract Infections
- Substances
- Azabicyclo Compounds · Anti-Bacterial Agents · Ceftibuten
- Therapy
- Administration, Oral
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- AdvanTIG-105: a phase I/Ib dose-expansion study of ociperlimab plus tislelizumab with or without chemotherapy in metastatic non-small cell lung cancer and extensive-stage small cell lung cancer. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms · Small Cell Lung Carcinoma
- Substances
- Antibodies, Monoclonal, Humanized
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- Expanded antigen-specific donor regulatory T cells for GVHD prevention. ↗
- Disease
- Graft vs Host Disease
- Substances
- Sirolimus
- Therapy
- Hematopoietic Stem Cell Transplantation · Transplantation, Homologous
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma. ↗
- Disease
- Multiple Myeloma
- Substances
- B-Cell Maturation Antigen · Receptors, Chimeric Antigen
- Therapy
- Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Preclinical and clinical evaluation of systemic danegaptide for the treatment of nonproliferative diabetic retinopathy. ↗
- Disease
- Diabetic Retinopathy · Macular Edema
- Substances
- Vascular Endothelial Growth Factor A · Connexin 43
- Phase 1 study of KHK2455, a long-acting, potent and selective IDO1 inhibitor, in combination with avelumab in patients with locally advanced or metastatic urothelial carcinoma. ↗
- Disease
- Urinary Bladder Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized · Indoleamine-Pyrrole 2,3,-Dioxygenase
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Factors impacting protective immunity conferred by vaccination with adeno-associated virus-like particles displaying human papillomavirus L2 residues 17-36. ↗
- Substances
- Papillomavirus Vaccines · Antibodies, Viral · Antibodies, Neutralizing
- Therapy
- Vaccination
- Research area
- HPV Vaccination and Public Health
- E7389-LF as a first-line chemotherapy for patients with metastatic/advanced HER2-negative breast cancer: results from the phase 1 dose-expansion part of study 114. ↗
- Disease
- Breast Neoplasms
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- SYS6010, epidermal growth factor receptor-targeting antibody-drug conjugate for advanced non-small cell lung cancer: A phase 1 trial. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- ErbB Receptors · Immunoconjugates · Antibodies, Monoclonal, Humanized
- A single-arm prospective phase I trial of 68Ga-PFBC01 PET/CT for multiple myeloma B cell maturation antigen imaging. ↗
- Disease
- Multiple Myeloma
- Substances
- B-Cell Maturation Antigen · Gallium Radioisotopes · Radiopharmaceuticals
- Tumoral and Systemic Immune Correlates of Response to Concurrent Pembrolizumab and Chemoradiotherapy in Patients with Resected High-Risk Head and Neck Squamous Cell Carcinoma. ↗
- Disease
- Squamous Cell Carcinoma of Head and Neck · Head and Neck Neoplasms
- Substances
- Antibodies, Monoclonal, Humanized · Tumor Suppressor Protein p53 · B7-H1 Antigen
- Therapy
- Chemoradiotherapy
- Research area
- Survival Outcomes in Cancer Therapy
- The First-in-Human ENCIT01 Trial Comparing Second- versus Third-Generation L1CAM-specific CAR T Cells in Patients with Primary Refractory or Relapsed Neuroblastoma. ↗
- Disease
- Neuroblastoma
- Substances
- Neural Cell Adhesion Molecule L1 · Receptors, Chimeric Antigen · Receptors, Antigen, T-Cell
- Therapy
- Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Transcriptomic analysis of a phase 1 trial for intraperitoneal monocytes plus IFNs in ovarian cancer reveals support and recruitment of cell-mediated immunity. ↗
- Disease
- Ovarian Neoplasms
- Substances
- Interferon-gamma · Interferon-alpha
- Research area
- Immunotherapy and Tumor Microenvironment Dynamics
- Phase 1/1b open-label, first-in-human study of HER2×CD3×CD28 trispecific T-cell engager (SAR443216) in participants with R/R HER2-expressing solid tumors. ↗
- Disease
- Neoplasms
- Substances
- Antibodies, Bispecific
- Research area
- Survival Outcomes in Cancer Therapy
- CAR T-cell therapy as a definitive consolidation for older adults with B-ALL in first complete remission. ↗
- Disease
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
- Substances
- Receptors, Chimeric Antigen · Receptors, Antigen, T-Cell
- Therapy
- Remission Induction · Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Safe Accelerated Venetoclax Escalation: a phase 1b study of obinutuzumab plus venetoclax with daily ramp-up in CLL. ↗
- Disease
- Tumor Lysis Syndrome
- Substances
- Bridged Bicyclo Compounds, Heterocyclic · Sulfonamides · Antibodies, Monoclonal, Humanized
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Synthetic long peptide and DNA personalized cancer vaccines induce robust neoantigen-specific T cell responses in pancreatic cancer. ↗
- Disease
- Pancreatic Neoplasms · Carcinoma, Pancreatic Ductal
- Substances
- Cancer Vaccines · Antigens, Neoplasm · Vaccines, DNA
- Therapy
- Precision Medicine
- Research area
- Survival Outcomes in Cancer Therapy
- A novel triple-knockout allogeneic BCMA CAR T-cell therapy (CT0590) for multiple myeloma: preclinical and phase 1 study. ↗
- Disease
- Multiple Myeloma
- Substances
- B-Cell Maturation Antigen · Receptors, Chimeric Antigen · NK Cell Lectin-Like Receptor Subfamily C
- Therapy
- Immunotherapy, Adoptive · Transplantation, Homologous
- Arlocabtagene autoleucel: a GPRC5D-targeted CAR T-cell therapy for heavily pretreated relapsed/refractory multiple myeloma. ↗
- Disease
- Multiple Myeloma
- Substances
- Receptors, Chimeric Antigen · Receptors, G-Protein-Coupled
- Therapy
- Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Daraxonrasib for Previously Treated RAS-Mutant Non-Small-Cell Lung Cancer. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Antineoplastic Agents · Piperazines · Proto-Oncogene Proteins p21(ras)
- Therapy
- Drug Administration Schedule · Administration, Oral
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Safety and Clinical Outcomes of a First-in-Human Trial of Point-of-Care Manufactured Trispecific CAR T Cells Targeting CD19, CD20, and CD22. ↗
- Disease
- Lymphoma, B-Cell
- Substances
- Sialic Acid Binding Ig-like Lectin 2 · Receptors, Chimeric Antigen
- Therapy
- Immunotherapy, Adoptive
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Clinical features and management of GPRC5D-associated adverse events in novel GPRC5D × CD3 bispecific talquetamab-treated relapsed/refractory multiple myeloma patients: the MonumenTAL-1 China cohort experience. ↗
- Disease
- Multiple Myeloma
- Substances
- Receptors, G-Protein-Coupled · Antibodies, Bispecific
- Research area
- Survival Outcomes in Cancer Therapy
- Treatment of multiple sclerosis with peptide-coupled red blood cells induces antigen-specific T regulatory cells. ↗
- Disease
- Multiple Sclerosis
- Substances
- Peptides · Autoantigens
- SHR-A2102, a nectin-4 directed antibody-drug conjugate, in patients with pretreated advanced solid tumours: a multicentre, single-arm, phase 1 trial. ↗
- Disease
- Neoplasms
- Substances
- Immunoconjugates · Nectins · Antibodies, Monoclonal, Humanized
- Research area
- Survival Outcomes in Cancer Therapy
- Effect of a Novel GLP-1 Analogue Ecnoglutide on the Pharmacokinetics of Rosuvastatin and Digoxin in Healthy Participants. ↗
- Substances
- Rosuvastatin Calcium · Digoxin · Glucagon-Like Peptide 1
- Research area
- Diabetes Management and Cardiovascular Outcomes
- A clinical study on the efficacy of a novel herbal medicine cocktail in enhancing HIFU treatment for adenomyosis: a pilot randomized controlled trial. ↗
- Disease
- Adenomyosis
- Substances
- Drugs, Chinese Herbal
- Therapy
- High-Intensity Focused Ultrasound Ablation
- Caregiver App Use and Child Behavioral Adherence in Relation to Obesity-Related Outcomes in an mHealth App-Assisted Childhood Obesity Intervention: Secondary Analysis of a Cluster Randomized Trial. ↗
- Research area
- Obesity and Metabolic Disorders
- Effectiveness of a novel low-level laser therapy protocol in managing breast cancer-related lymphedema. ↗
- Disease
- Breast Neoplasms
- Therapy
- Low-Level Light Therapy
- TACE combined with apatinib versus TACE alone for unresectable hepatocellular carcinoma in China: a cost-effectiveness and budget impact analysis. ↗
- Disease
- Carcinoma, Hepatocellular · Liver Neoplasms
- Substances
- Pyridines · Antineoplastic Agents
- Therapy
- Chemoembolization, Therapeutic · Combined Modality Therapy
- Effect of exercise on memory function and daily activities after colorectal cancer surgery: an exploratory secondary analysis from the randomised trial PHYSSURG-C. ↗
- Disease
- Colorectal Neoplasms
- Therapy
- Activities of Daily Living · Exercise Therapy
- Research area
- Obesity and Metabolic Disorders
- Randomized, placebo-controlled trial of N-acetylcysteine in Parkinson's disease patients: a pilot study. ↗
- Disease
- Parkinson Disease
- Substances
- Acetylcysteine · Antiparkinson Agents · Levodopa
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Acceptance and perceived efficacy of intraoral versus extraoral photobiomodulation for oral mucositis prevention in pediatric patients. ↗
- Disease
- Stomatitis · Neoplasms
- Substances
- Antineoplastic Agents
- Therapy
- Low-Level Light Therapy
- Research area
- Psychosocial Impact of Cancer and HIV
- Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk. ↗
- Disease
- Stroke · Embolism
- Substances
- Anticoagulants · Factor Xa Inhibitors
- Therapy
- Administration, Oral
- Research area
- Anticoagulation Strategies in Stroke
- Effect of Delayed Antiretroviral Therapy Initiation on Anti-CD4 Autoantibodies in Antiretroviral Therapy-Naive People With HIV. ↗
- Disease
- HIV Infections
- Substances
- Autoantibodies · Anti-HIV Agents
- Therapy
- Treatment Delay
- Research area
- Psychosocial Impact of Cancer and HIV
- A workbook- and audio-administered, telephone-guided, low-intensity cognitive behavioural therapy intervention (EJDeR) for parents of persons treated for cancer during childhood: protocol for the CHANGE-pilot randomised controlled trial. ↗
- Disease
- Neoplasms
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Real-Time Artificial Intelligence Diagnostic Copilot in Simulated Primary Care Consultations: Randomized Simulation Study. ↗
- Research area
- Psychosocial Impact of Cancer and HIV
- The Digital Diabetes Patient Reminder Tool for Adults With Type 2 Diabetes: Protocol for a Proof-of-Concept Randomized Controlled Trial. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- Glycated Hemoglobin
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Prevention of Rebleeding in Colonic Diverticular Bleeding Using Orengedokuto: Protocol for a Double-Blind Randomized Controlled Trial. ↗
- Substances
- Drugs, Chinese Herbal
- Therapy
- Hemostasis, Endoscopic
- Implementing the MATILDA intervention to enhance community participation for older adults with intellectual disability: A feasibility randomised controlled trial and RE-AIM guided process evaluation. ↗
- Research area
- Psychosocial Impact of Cancer and HIV
- Effect of Vutrisiran According to Baseline Tafamidis Use in Transthyretin Amyloidosis With Cardiomyopathy: Insights From HELIOS-B. ↗
- Disease
- Cardiomyopathies · Amyloid Neuropathies, Familial
- Substances
- Benzoxazoles · RNA, Small Interfering
- Therapy
- RNAi Therapeutics
- Research area
- Heart Failure and Renal Insufficiency Management
- Influence of Disease-Modifying Therapy on the Efficacy of Vutrisiran in Transthyretin Cardiac Amyloidosis. ↗
- Disease
- Amyloid Neuropathies, Familial · Cardiomyopathies
- Substances
- Benzoxazoles · Sodium-Glucose Transporter 2 Inhibitors
- Therapy
- RNAi Therapeutics
- Research area
- Heart Failure and Renal Insufficiency Management
- Stereotactic Body Radiotherapy vs Moderately Hypofractionated IMRT for Localized Intermediate-Risk Prostate Cancer: A Randomized Clinical Trial. ↗
- Disease
- Prostatic Neoplasms
- Therapy
- Radiosurgery · Radiotherapy, Intensity-Modulated
- Research area
- Survival Outcomes in Cancer Therapy
- Treating socket discharge and discomfort: a crossover randomised trial of vitamin A ointment, low-dose steroid eyedrops and artificial tears. ↗
- Substances
- Ointments · Vitamin A · Lubricant Eye Drops
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Effect of periprocedural antithrombotic medication on functional outcome and symptomatic intracranial hemorrhage in patients with carotid tandem lesions. ↗
- Disease
- Carotid Stenosis · Ischemic Stroke
- Substances
- Fibrinolytic Agents · Aspirin · Heparin
- Therapy
- Endovascular Procedures
- Research area
- Anticoagulation Strategies in Stroke
- Validation of the newly introduced Deauville score 5a for patients treated for advanced-stage classic Hodgkin lymphoma. ↗
- Disease
- Hodgkin Disease
- Substances
- Cyclophosphamide · Doxorubicin · Etoposide
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Survival Outcomes in Cancer Therapy
- API-CAT investigators' decisions on anticoagulation following extended treatment for cancer-associated thrombosis. ↗
- Disease
- Neoplasms · Venous Thromboembolism
- Substances
- Pyrazoles · Pyridones · Factor Xa Inhibitors
- Therapy
- Secondary Prevention
- Research area
- Anticoagulation Strategies in Stroke
- Heart Rate and Cardiovascular Outcomes in Post-Myocardial Infarction Patients Treated by β-Blockers: A Secondary Analysis of the ABYSS Trial. ↗
- Disease
- Stroke
- Substances
- Adrenergic beta-Antagonists
- Research area
- Heart Failure and Renal Insufficiency Management
- Implementation of a patient-centred complex intervention to improve Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care (the IMA-cRCT study): a mixed-methods process evaluation. ↗
- Disease
- Cardiovascular Diseases · Diabetes Mellitus
- Research area
- Psychosocial Impact of Cancer and HIV
- The effect of 0.1% topical ciclosporin a for 12-weeks on the ocular surface innate and adaptive immune response in dry eye disease: protocol for a randomized controlled clinical trial. ↗
- Disease
- Dry Eye Syndromes
- Substances
- Cyclosporine · Immunosuppressive Agents · Ophthalmic Solutions
- Therapy
- Administration, Topical
- Effect of esketamine on postoperative pulmonary complications after radical surgery for lung cancer: A randomized double-blind controlled trial. ↗
- Disease
- Lung Neoplasms
- Therapy
- Length of Stay · Thoracoscopy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- High potency and water dispersible Boswellia extract reduces pain and inflammation in subjects with osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trial. ↗
- Disease
- Osteoarthritis, Knee
- Substances
- Plant Extracts · C-Reactive Protein
- Therapy
- Phytotherapy
- Research area
- Obesity and Metabolic Disorders
- Early-life serum protein profiles associated with bronchopulmonary dysplasia in extremely preterm infants. ↗
- Disease
- Bronchopulmonary Dysplasia
- Substances
- Blood Proteins
- Ayurvedic Treatment for Lumbar Disc Herniation With Radiculopathy: Protocol for a Randomized Controlled Trial. ↗
- Disease
- Radiculopathy
- Therapy
- Medicine, Ayurvedic
- Machine learning identifies microbiome and clinical predictors of sustained weight loss following prolonged fasting. ↗
- Research area
- Obesity and Metabolic Disorders
- Effect of simvastatin versus calcium hydroxide intracanal medications on postoperative pain and cytokine modulation in symptomatic apical periodontitis: a randomized controlled trial. ↗
- Disease
- Periapical Periodontitis
- Substances
- Simvastatin · Calcium Hydroxide · Interleukin-6
- Rituximab Maintenance Added to Ibrutinib-Containing Therapy in Younger, Untreated Patients With Mantle Cell Lymphoma: Results From the TRIANGLE Trial. ↗
- Disease
- Lymphoma, Mantle-Cell
- Substances
- Piperidines · Adenine · Rituximab
- Therapy
- Antineoplastic Combined Chemotherapy Protocols · Maintenance Chemotherapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- OnabotulinumtoxinA for Painful Foot Dystonia in Parkinson Disease: A Randomized, Double-Blind, Placebo-Controlled Trial. ↗
- Disease
- Parkinson Disease
- Substances
- Botulinum Toxins, Type A · Neuromuscular Agents
- Short-term adjunctive use of a liposomal tear substitute after repeated intravitreal therapy: a randomized pilot study. ↗
- Disease
- Dry Eye Syndromes · Macular Degeneration
- Substances
- Liposomes · Angiogenesis Inhibitors · Ophthalmic Solutions
- Therapy
- Intravitreal Injections
- Colonoscopy Intervals and Colorectal Cancer Incidence after Adenoma Removal. ↗
- Disease
- Adenoma · Colorectal Neoplasms
- Therapy
- Colonoscopy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Effects of a Group-Based Cognitive Behavioral Therapy for Sleep in Nursing Students: Pilot Randomized Controlled Trial. ↗
- Disease
- Sleep Initiation and Maintenance Disorders
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Virtual Reality-Assisted Therapy Compared to Cognitive Behavioral Therapy for Patients With Treatment-Resistant Schizophrenia: Assessor-Blind Randomized Controlled Trial. ↗
- Disease
- Schizophrenia, Treatment-Resistant · Psychotic Disorders
- Single-session extraoral photobiomodulation reduces early postoperative pain but not edema or trismus after impacted mandibular third molar extraction: a randomized controlled trial. ↗
- Disease
- Tooth, Impacted
- Therapy
- Low-Level Light Therapy · Tooth Extraction
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Seroefficacy of a 10-valent pneumococcal conjugate vaccine (Pneumosil®) compared with other pneumococcal conjugate vaccines in children. ↗
- Disease
- Pneumococcal Infections
- Substances
- Pneumococcal Vaccines · Antibodies, Bacterial · Immunoglobulin G
- Therapy
- Immunization, Secondary · Vaccination
- A novel inactivated vaccine for cross-protection against Actinobacillus pleuropneumoniae in pigs. ↗
- Disease
- Actinobacillus Infections · Swine Diseases
- Substances
- Bacterial Vaccines · Bacterial Proteins · Hemolysin Proteins
- Sodium Bicarbonate for Critically Ill Adults with Metabolic Acidosis and Shock. ↗
- Disease
- Acidosis · Acute Kidney Injury
- Substances
- Sodium Bicarbonate · Vasoconstrictor Agents
- Therapy
- Infusions, Intravenous · Renal Replacement Therapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Repeated switching between biosimilar ABP 654 and reference ustekinumab in patients with moderate-to-severe plaque psoriasis: a randomized double-blinded clinical trial to support interchangeability. ↗
- Disease
- Psoriasis
- Substances
- Ustekinumab · Biosimilar Pharmaceuticals · Dermatologic Agents
- Therapy
- Drug Substitution · Injections, Subcutaneous
- Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in elderly patients undergoing non-cardiac and non-neurosurgical procedures: protocol for a multicentre, double-blind, randomized, controlled trial. ↗
- Disease
- Hypotension
- Substances
- Phenylephrine · Ephedrine · Vasoconstrictor Agents
- Therapy
- Infusions, Intravenous · Intraoperative Care
- Research area
- Postoperative Outcomes in Robotic Surgery
- A prospective randomized controlled pilot study of gut microbiome modulation by Nigella sativa seed oil and thymoquinone metabolism in healthy volunteers: implications for gastrointestinal surgery. ↗
- Substances
- Plant Oils · Benzoquinones · RNA, Ribosomal, 16S
- Effect of demographic characteristics on the outcome of prostate cancer salvage radiotherapy: Analysis from a randomized controlled trial. ↗
- Disease
- Prostatic Neoplasms
- Substances
- Cyclobutanes · Carboxylic Acids
- Therapy
- Salvage Therapy · Prostatectomy
- Research area
- Postoperative Outcomes in Robotic Surgery
- Effects of 12 weeks of resistance and concurrent training with graded protein intakes on lipid profile, kidney and liver biomarkers in middle-aged to older women. ↗
- Substances
- Dietary Proteins · Lipids · Triglycerides
- Therapy
- Resistance Training
- Research area
- Obesity and Metabolic Disorders
- Transabdominal lumbar approach (TALA) versus retroperitoneal approach for robot-assisted renal surgery: a prospective randomised controlled trial. ↗
- Disease
- Kidney Neoplasms
- Therapy
- Robotic Surgical Procedures · Nephrectomy
- Research area
- Postoperative Outcomes in Robotic Surgery
- Add-On PCSK9 Inhibitor Therapy for Acute Stroke Attributable to Intracranial Atherosclerosis: A Randomized Clinical Trial. ↗
- Disease
- Intracranial Arteriosclerosis · Ischemic Stroke · Stroke
- Substances
- PCSK9 Inhibitors · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Proprotein Convertase 9
- Therapy
- Drug Therapy, Combination
- Accelerated Diagnostic Pathways for Suspected Acute Coronary Syndrome in Practice: A Randomized Trial of 0/1-Hour vs 0/3-Hour Troponin Testing. ↗
- Disease
- Acute Coronary Syndrome
- Substances
- Troponin
- Research area
- Heart Failure and Renal Insufficiency Management
- Insights from changes in NDEV biomarkers of metabolism: effects of PPARγ and GLP1 receptor agonists on brain metabolism. ↗
- Disease
- Insulin Resistance · Alzheimer Disease
- Substances
- Pioglitazone · PPAR-gamma Agonists · Liraglutide
- Effects of testosterone-augmented multimodal exercise intervention in spinal cord injury: a randomized controlled trial. ↗
- Disease
- Spinal Cord Injuries
- Substances
- Testosterone
- Therapy
- Exercise Therapy · Combined Modality Therapy
- Research area
- Obesity and Metabolic Disorders
- Validating national registry data for randomized trials: comparison of registry-derived cardiovascular events with and without adjudication in the BETAMI-DANBLOCK trial. ↗
- Disease
- Heart Failure
- Substances
- Adrenergic beta-Antagonists
- Research area
- Heart Failure and Renal Insufficiency Management
- Fourteen-Day Amoxicillin- or Tetracycline-Containing Bismuth Quadruple Therapy versus 14-Day Metronidazole-Based Triple Therapy as the Treatment for Clarithromycin-Resistant Helicobacter pylori Infection: A Multicenter Randomized Controlled Trial. ↗
- Disease
- Helicobacter Infections
- Substances
- Metronidazole · Tetracycline · Bismuth
- Therapy
- Drug Therapy, Combination · Drug Administration Schedule
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Impact of Diabetes on Outcomes of Contemporary PCI Guided by OCT vs Angiography: The ILUMIEN IV Trial. ↗
- Disease
- Coronary Artery Disease · Diabetes Mellitus
- Therapy
- Percutaneous Coronary Intervention
- Research area
- Machine Learning in Cardiovascular Risk Assessment
- Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption. ↗
- Therapy
- Diet, Carbohydrate-Restricted
- Effect of Semaglutide on the Inflammatory Biomarker High-Sensitivity CRP in Patients With Established Cardiovascular Disease and Overweight or Obesity in SELECT: A Prespecified Secondary Analysis. ↗
- Disease
- Cardiovascular Diseases
- Substances
- Glucagon-Like Peptides · C-Reactive Protein
- Research area
- Obesity and Metabolic Disorders
- Bempedoic Acid and First and Recurrent Limb Outcomes in Statin-Intolerant Patients With Peripheral Artery Disease: Insights From the CLEAR Outcomes Trial. ↗
- Disease
- Peripheral Arterial Disease
- Substances
- Fatty Acids · Dicarboxylic Acids · Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Clopidogrel vs Aspirin According to Diabetes Mellitus: A Prespecified Analysis of the SMART-CHOICE 3 Trial. ↗
- Disease
- Diabetes Mellitus · Coronary Artery Disease
- Substances
- Clopidogrel · Platelet Aggregation Inhibitors · Aspirin
- Therapy
- Percutaneous Coronary Intervention · Dual Anti-Platelet Therapy
- Research area
- Anticoagulation Strategies in Stroke
- Sex differences in brain frailty measures and outcomes after endovascular thrombectomy: ESCAPE-NA1 analysis. ↗
- Disease
- Ischemic Stroke
- Therapy
- Thrombectomy · Endovascular Procedures
- Research area
- Anticoagulation Strategies in Stroke
- Early-event pathways to 6-month death or dependency after ischemic stroke: Secondary analysis of the international stroke trial. ↗
- Disease
- Ischemic Stroke · Brain Ischemia · Stroke
- Substances
- Aspirin · Fibrinolytic Agents · Heparin
- Research area
- Anticoagulation Strategies in Stroke
- The efficacy of deslorelin implants in neutered male dogs that sexually attract other male dogs: a randomized controlled trial. ↗
- Substances
- Drug Implants · Follicle Stimulating Hormone · Luteinizing Hormone
- Therapy
- Orchiectomy
- Clinical outcomes of acupuncture combined with Jieyu Huoxue Formula in optic atrophy: effects on hemorheology and retrobulbar blood flow. ↗
- Disease
- Optic Atrophy
- Substances
- Drugs, Chinese Herbal
- Therapy
- Acupuncture Therapy · Combined Modality Therapy
- Efficacy and safety of Mudan granules for treatment of diabetic peripheral neuropathy: a multicenter, double-blind, placebo-controlled, randomized, clinical trial. ↗
- Disease
- Diabetic Neuropathies
- Substances
- Drugs, Chinese Herbal · Vitamin B 12
- Efficacy and Safety of Celecoxib Combined With Jintiange Capsules for the Treatment of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ↗
- Disease
- Osteoarthritis, Knee
- Substances
- Celecoxib · Drugs, Chinese Herbal · Anti-Inflammatory Agents, Non-Steroidal
- Therapy
- Medicine, Chinese Traditional · Drug Therapy, Combination
- Effect of self-activating phthalocyanine gel on palatal donor site healing, inflammatory biomarkers, somatosensory and patient-centered outcomes: a randomized split-mouth clinical trial. ↗
- Substances
- Gels · Indoles · Isoindoles
- Effects of six weeks of guanidinoacetic acid supplementation with and without creatine monohydrate on cognitive function and markers of health in healthy adults. ↗
- Substances
- Creatine · Glycine
- A bimodal large language model reduces misalignment in patient education: A double-blinded randomized trial. ↗
- Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial. ↗
- Substances
- Ketamine · Analgesics
- Therapy
- Combined Modality Therapy · Infusions, Intravenous
- Effects of Esketamine on Postoperative Hospital Anxiety and Depression Scale Scores in Patients Undergoing Laparoscopic Radical Resection for Colorectal Cancer. ↗
- Disease
- Colorectal Neoplasms
- Substances
- Ketamine · Interleukin-6
- Therapy
- Laparoscopy · Length of Stay
- Research area
- Postoperative Outcomes in Robotic Surgery
- Assessment of the role and effectiveness of nurse-led multimodal intervention in the rehabilitation of dysphagia in patients with brain tumors. ↗
- Disease
- Deglutition Disorders · Brain Neoplasms
- Therapy
- Combined Modality Therapy
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Evaluating a coaching intervention for Dementia Care Practice Recommendations in care communities: a cluster randomized controlled trial. ↗
- Disease
- Dementia
- Novel Proactive Speech-Language Intervention Is More Effective Than Usual Care: Randomized Controlled Trial of Babble Boot Camp for Infants With Classic Galactosemia. ↗
- Disease
- Galactosemias
- Therapy
- Speech Therapy · Language Therapy
- Probiotic supplementation increases fecal TLR4 agonists without improving disease activity in juvenile idiopathic arthritis: a randomized placebo-controlled trial. ↗
- Disease
- Arthritis, Juvenile
- Substances
- Toll-Like Receptor 4 · Cytokines · Toll-Like Receptor Agonists
- Autophagy activation in granulosa cells as a mechanism of astaxanthin action: evidence from a pilot randomised trial in PMOS-associated infertility. ↗
- Disease
- Polycystic Ovary Syndrome · Infertility, Female
- Substances
- Xanthophylls
- Multi-centre randomised controlled feasibility trial with embedded process evaluation of a samba percussion intervention for people living with Parkinson's disease: a protocol for the Sparky Samba trial. ↗
- Disease
- Parkinson Disease
- A Multimethod Evaluation to Assess Feasibility, Acceptability, and Preliminary Efficacy of HPVVaxFacts, a Tailored Mobile Web App, for Parents With Unvaccinated Children: Pilot 2-Arm Randomized Controlled Trial. ↗
- Substances
- Papillomavirus Vaccines
- Therapy
- Vaccination
- Research area
- HPV Vaccination and Public Health
- Effects of exercise on muscle strength and characteristics in rheumatic diseases and sarcopenia: Protocol for the Care for Muscle (C4M) Study. ↗
- Disease
- Rheumatic Diseases · Arthritis, Rheumatoid · Osteoarthritis
- Therapy
- Exercise Therapy · Resistance Training
- Complete Revascularization Guided by Functional Coronary Angiography in STEMI. ↗
- Disease
- Acute Kidney Injury · Coronary Artery Disease · Stroke
- Substances
- Contrast Media
- Therapy
- Myocardial Revascularization · Percutaneous Coronary Intervention
- Research area
- Anticoagulation Strategies in Stroke
- COMBI-I: Long-Term Overall Survival With Spartalizumab Plus Dabrafenib and Trametinib in BRAF V600-Mutant Advanced Melanoma. ↗
- Disease
- Melanoma · Skin Neoplasms
- Substances
- Pyrimidinones · Imidazoles · Pyridones
- Therapy
- Antineoplastic Combined Chemotherapy Protocols
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Implementation outcomes of a dementia-focused intervention for family care partners and clinicians in home hospice care. ↗
- Disease
- Dementia
- Therapy
- Hospice Care
- Research area
- Psychosocial Impact of Cancer and HIV
- Magnesium administration for vasospasm prevention in acute aneurysmal SAH: a multicenter randomized controlled trial. ↗
- Disease
- Vasospasm, Intracranial
- Substances
- Magnesium Sulfate
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- A qualitative study of cancer survivors' exercise behaviour 4 months after a telerehabilitation program. ↗
- Disease
- Neoplasms
- Therapy
- Telerehabilitation · Exercise Therapy
- Research area
- Obesity and Metabolic Disorders
- Effect of Various Types of Remineralizing Agents on the Remineralization of Mild and Moderate Defects Caused by Molar-Incisor Hypomineralization in Mexican Schoolchildren: A 12-month Follow-up Randomized Clinical Trial. ↗
- Disease
- Molar Hypomineralization · Dental Enamel Hypoplasia
- Substances
- Toothpastes · Cariostatic Agents · Caseins
- Functional Reading Activities to Motivate and Empower: Maintenance of Reading Outcomes for Young Adults With Intellectual and Developmental Disabilities Following a Randomized Controlled Trial. ↗
- Disease
- Developmental Disabilities
- Comparing Traditional Motor Speech Practice to Contextualized Speech Practice in Preschoolers With Childhood Apraxia of Speech. ↗
- Therapy
- Speech Therapy
- Dose-Controlled Script Training for Aphasia: A Quasi-Randomized Pilot Clinical Trial Examining Treatment Frequency. ↗
- Disease
- Stroke
- Therapy
- Stroke Rehabilitation · Therapy, Computer-Assisted
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- The clinical relevance of regional lymph node microarchitecture in oesophageal cancer patients - Results from the UK MRC OE02 trial. ↗
- Disease
- Esophageal Neoplasms
- Therapy
- Neoadjuvant Therapy · Esophagectomy
- Research area
- Survival Outcomes in Cancer Therapy
- USleep: efficacy of app-based audio interventions to improve sleep disturbance in working adults, a multi-arm randomized controlled trial. ↗
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Daridorexant in severe obstructive sleep apnea: effects on sleep-disordered breathing and sleep. ↗
- Disease
- Sleep Apnea, Obstructive
- Substances
- Pyrrolidines · Imidazoles
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Low-dose ticagrelor combined with aspirin for preventing early neurological deterioration in patients with high-risk non-disabling ischemic cerebrovascular events: a multicenter, prospective, randomized, open-label, clinical trial. ↗
- Disease
- Brain Ischemia · Ischemic Stroke
- Substances
- Aspirin · Ticagrelor · Platelet Aggregation Inhibitors
- Therapy
- Drug Therapy, Combination
- Research area
- Anticoagulation Strategies in Stroke
- The effect of a smartphone-based educational intervention on the supportive care needs of family caregivers of patients with colorectal cancer: a randomized controlled trial. ↗
- Disease
- Colorectal Neoplasms
- Research area
- Psychosocial Impact of Cancer and HIV
- Effects of the 'ReacStep' training program on balance recovery and fall risk factors in older people: an assessor-blinded randomised controlled trial. ↗
- Therapy
- Resistance Training
- Effect of repeated exposure to an identical multi-user virtual reality anaphylaxis scenario on paramedic trainee performance: a randomized controlled trial. ↗
- Disease
- Anaphylaxis
- Substances
- Epinephrine
- Scaffolded AI-Supported Problem-Based Learning for Medical Interns: Exploratory Retrospectively Registered Randomized Controlled Evaluation With a Voluntary Feasibility Follow-Up. ↗
- Behavioral Modification as a Putative Mediator of Digital Therapeutic Response in Temporomandibular Disorders: Secondary Analysis of a Multicenter Sham-Controlled Randomized Trial. ↗
- Disease
- Temporomandibular Joint Disorders
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Effects of erector spinae plane block on postoperative pain in patients undergoing implant-based breast reconstruction for breast cancer: a randomized controlled trial. ↗
- Disease
- Breast Neoplasms
- Substances
- Dexmedetomidine · Ropivacaine · Analgesics, Opioid
- Therapy
- Nerve Block · Mammaplasty
- Research area
- Psychosocial Impact of Cancer and HIV
- User Engagement and Feature Preferences in an AI-Powered mHealth Intervention for Diabetes Prevention: Secondary Analysis of a Randomized Controlled Trial. ↗
- Disease
- Diabetes Mellitus, Type 2 · Prediabetic State
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Bifidobacterium animalis subsp. lactis V9 overcomes CYFRA 21-1-linked immunochemotherapy resistance in NSCLC via microbial metabolites. ↗
- Disease
- Carcinoma, Non-Small-Cell Lung · Lung Neoplasms
- Substances
- Antigens, Neoplasm · Keratin-19
- Therapy
- Immunotherapy
- Use of indocyanine green fluorescence versus patent blue V dye for sentinel lymph node biopsy in early breast cancer, a randomized controlled trial. ↗
- Disease
- Breast Neoplasms
- Substances
- Indocyanine Green · Rosaniline Dyes · Coloring Agents
- Therapy
- Sentinel Lymph Node Biopsy · Lymph Node Excision
- Research area
- Survival Outcomes in Cancer Therapy
- Characteristics of post-exercise responders versus non-responders following aerobic or isometric exercise in physically inactive adults of African and South Asian descent with high-normal blood pressure or grade I hypertension. ↗
- Disease
- Hypertension · Post-Exercise Hypotension
- Research area
- Obesity and Metabolic Disorders
- The effect of metformin on the pharmacokinetics of rifampicin, isoniazid, and pyrazinamide in adults with tuberculosis. ↗
- Disease
- HIV Infections · Tuberculosis
- Substances
- Metformin · Pyrazinamide · Rifampin
- Comparative Effectiveness of Oral Ivermectin, 1% Permethrin Shampoo, and 4% Dimethicone Liquid Gel in Treatment of Pediculosis Capitis among School Children in Chachoengsao Province, Thailand. ↗
- Disease
- Lice Infestations
- Substances
- Permethrin · Ivermectin · Insecticides
- Therapy
- Administration, Oral
- PCa Detection in PI-RADS 4 and 5 Lesions: Comparison of [68Ga]Ga-PSMA-11 PET/CT-Guided Robot-Assisted Biopsy Versus mpMRI Cognitive-Fusion TRUS-Guided Prostate Biopsy. ↗
- Disease
- Prostatic Neoplasms
- Substances
- Gallium Radioisotopes · Edetic Acid · Gallium Isotopes
- Therapy
- Image-Guided Biopsy · Robotic Surgical Procedures
- How Following Medical Artificial Intelligence Advice Can Mitigate Malpractice Liability: Cross-National Insights from a Randomized Trial. ↗
- Balanced Fluid or 0.9% Saline in Children Treated for Septic Shock. ↗
- Disease
- Acute Kidney Injury
- Substances
- Crystalloid Solutions · Isotonic Solutions · Saline Solution
- Therapy
- Fluid Therapy · Renal Replacement Therapy
- Hypertension in a Randomized Trial of Dolutegravir- Versus Efavirenz-Based Antiretroviral Therapy in Pregnant and Postpartum Women with HIV. ↗
- Disease
- HIV Infections · Pregnancy Complications, Infectious · Hypertension
- Substances
- Oxazines · Alkynes · Piperazines
- Therapy
- Antiretroviral Therapy, Highly Active
- Predictors of Treatment Failure in Children With HIV Starting First-line Antiretroviral Therapy in the ODYSSEY Trial. ↗
- Disease
- HIV Infections
- Substances
- Piperazines · Pyridones · Oxazines
- Therapy
- Antiretroviral Therapy, Highly Active
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Effects of transcutaneous electrical acupoint stimulation versus acupressure on the trajectories of multidimensional adverse reactions to chemotherapy in breast cancer patients: a secondary analysis of a randomized controlled trial. ↗
- Disease
- Breast Neoplasms
- Substances
- Antineoplastic Agents
- Therapy
- Transcutaneous Electric Nerve Stimulation · Acupuncture Points
- Research area
- Psychosocial Impact of Cancer and HIV
- Effect of a 6-month low-carbohydrate diet on the circulating fatty acid composition in patients with type 2 diabetes: a secondary analysis of an open-label randomized controlled trial. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- Fatty Acids · Fatty Acids, Monounsaturated · Phospholipids
- Therapy
- Diet, Carbohydrate-Restricted
- Effect of a person-centered care intervention on return and sustained reengagement after treatment interruptions from HIV care in Zambia: A post-hoc analysis of a stepped-wedged cluster randomized trial. ↗
- Disease
- HIV Infections
- Substances
- Anti-HIV Agents
- Therapy
- Retention in Care
- Research area
- Psychosocial Impact of Cancer and HIV
- A 12-week, double-blind, quasi-randomized, placebo-controlled study to evaluate the efficacy and safety of Coleus forskohlii (Forcslim) on body weight loss. ↗
- Substances
- Plant Extracts · Triglycerides · Lipids
- Research area
- Obesity and Metabolic Disorders
- KangDuo surgical robot KD-SR-01 versus da Vinci Xi in robot-assisted colorectal cancer resection: oncologic outcomes at three years in a multicenter randomized trial. ↗
- Disease
- Colorectal Neoplasms
- Therapy
- Robotic Surgical Procedures
- Research area
- Survival Outcomes in Cancer Therapy
- Clopidogrel Versus Dual-Antiplatelet Therapy for Long-Term Maintenance After Coronary Stenting in Ischemic and Bleeding Birisk Patients With Acute Coronary Syndromes and Diabetes: A Prespecified Subgroup Analysis of the OPT-BIRISK Trial. ↗
- Disease
- Acute Coronary Syndrome · Diabetes Mellitus
- Substances
- Clopidogrel · Platelet Aggregation Inhibitors · Aspirin
- Therapy
- Percutaneous Coronary Intervention · Dual Anti-Platelet Therapy
- Research area
- Anticoagulation Strategies in Stroke
- Effects of lavender oil preparation silexan on different symptoms of major depression - results from a randomized, controlled trial. ↗
- Substances
- Plant Oils · Antidepressive Agents · Oils, Volatile
- Haemodynamic responses to head-up tilt versus lower-body negative pressure in type 1 diabetes. ↗
- Disease
- Diabetes Mellitus, Type 1
- Therapy
- Lower Body Negative Pressure
- Comparative Effectiveness of Fluid Absorption Between Superabsorbent and Foam Dressings in Split-Thickness Skin-Graft Donor Sites: A Randomized Controlled Trial. ↗
- Disease
- Wounds and Injuries
- Therapy
- Skin Transplantation
- Effect of Kinetic Control Retraining on Electromyographic Activity of Trunk Muscles in Patients with Lumbosacral Radiculopathy: A Randomized Controlled Trial. ↗
- Disease
- Radiculopathy
- Therapy
- Physical Therapy Modalities
- Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial. ↗
- Disease
- COVID-19
- Substances
- Proton Pump Inhibitors · Pantoprazole
- Therapy
- Respiration, Artificial · COVID-19 Drug Treatment
- Research area
- Heart Failure and Renal Insufficiency Management
- Post-exercise rehydration: a randomized cross-over trial comparing a 100% fruit juice, a glucose-based sports drink, and water. ↗
- Substances
- Glucose · Water · Blood Glucose
- Therapy
- Fluid Therapy · Post-Exercise Recovery Techniques
- Investigating the Effects of Adding Explicit Teaching and/or Signing to Story-Based Vocabulary Intervention for School-Aged Children With (Developmental) Language Disorder. ↗
- Therapy
- Language Therapy
- Extended Use of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 1 Diabetes: 12-Month Extension of a Randomized Controlled Trial. ↗
- Disease
- Diabetes Mellitus, Type 1
- Substances
- Insulin · Hypoglycemic Agents · Blood Glucose
- Therapy
- Insulin Infusion Systems
- Research area
- Diabetes Management and Cardiovascular Outcomes
- App-based self-administered biofeedback for the prevention of episodic migraine: A randomized controlled trial. ↗
- Disease
- Migraine Disorders
- Therapy
- Biofeedback, Psychology
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Submucosal Lidocaine Injection in Colonic Endoscopic Submucosal Dissection: A Single-Center, Double-Blind, Randomized Controlled Trial. ↗
- Disease
- Colonic Neoplasms
- Substances
- Lidocaine · Anesthetics, Local
- Therapy
- Endoscopic Mucosal Resection · Injections
- Transvaginal Natural Orifice Transluminal Endoscopic Ovarian Cystectomy versus Laparoscopic Ovarian Cystectomy. A prospective quasi-randomized pilot study. ↗
- Disease
- Ovarian Cysts
- Therapy
- Laparoscopy · Natural Orifice Endoscopic Surgery
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Effectiveness of Yoga and Combined Exercise in Female With Rheumatoid Arthritis: Randomized Controlled Trial. ↗
- Disease
- Arthritis, Rheumatoid
- Therapy
- Yoga · Exercise Therapy
- Research area
- Obesity and Metabolic Disorders
- Improving Sleep and PTSD Outcomes in Service Members: A Randomized Controlled Trial Examining the Long-Term Effects of an Integrated Treatment. ↗
- Disease
- Stress Disorders, Post-Traumatic
- Enhancing Self Care Among Oral Cancer Survivors Using a Digital Approach: The Empowered Survivor Trial. ↗
- Disease
- Mouth Neoplasms · Oropharyngeal Neoplasms
- Therapy
- Self Care
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Acetate- Versus Lactate-Buffered Crystalloids for Prevention of Post-ERCP Pancreatitis in Patients Without Access to Rectal NSAIDs: A Multicentre Double-Blind Randomized Trial. ↗
- Disease
- Pancreatitis
- Substances
- Crystalloid Solutions · Anti-Inflammatory Agents, Non-Steroidal · Ringer's Lactate
- Therapy
- Cholangiopancreatography, Endoscopic Retrograde · Administration, Rectal
- Research area
- Obesity and Metabolic Disorders
- ALG-020572, an Antisense Oligonucleotide for the Treatment of Chronic Hepatitis B Virus Infection Discontinued for Drug-Induced Liver Injury. ↗
- Disease
- Chemical and Drug Induced Liver Injury
- Substances
- Antiviral Agents · Oligonucleotides, Antisense · Placebos
- Therapy
- Placebos
- Low-Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle-Aged and Older Adults: Study Protocol for a Triple-Blind, Randomised, Placebo-Controlled Trial. ↗
- Substances
- Flavonols · Flavonoids · Receptors, Urokinase Plasminogen Activator
- The Effect of Aromatherapy on Fatigue and Sleep Quality in Intensive Care Nurses: A Randomised Placebo-Controlled Trial. ↗
- Substances
- Oils, Volatile · Plant Oils
- Therapy
- Aromatherapy
- Technology choice, glycemic control and patient-reported outcome measures in adults with type 1 diabetes: A randomized crossover trial comparing a smart insulin pen with an automated insulin delivery system (EBIACE-1). ↗
- Disease
- Diabetes Mellitus, Type 1
- Substances
- Insulin · Hypoglycemic Agents · Glycated Hemoglobin
- Therapy
- Glycemic Control · Insulin Infusion Systems
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Predicting training outcomes for developmental dyslexia from EEG data. ↗
- Therapy
- Transcranial Direct Current Stimulation
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Protocol for the CLOCKS study: A 4-arm randomized controlled trial testing the independent and combined effects of 2 chronotherapies-early time-restricted eating and daytime bright light therapy-in adults with type 2 diabetes. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- Blood Glucose · Glycated Hemoglobin · Melatonin
- Therapy
- Phototherapy · Chronotherapy
- Vitamin D Deficiency During Pregnancy Is Associated With Greater LDL-C Increase, Elevated β-Hydroxybutyrate and Altered Neonatal Metabolic Markers-A Secondary, Pooled Analysis of the Randomized, Controlled Vitamin D and Lifestyle for Gestational Diabetes Prevention Trial (DALI). ↗
- Disease
- Vitamin D Deficiency · Diabetes, Gestational · Pregnancy Complications
- Substances
- 3-Hydroxybutyric Acid · Cholesterol, LDL · Vitamin D
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Financial incentives and health coaching to improve glycemic outcomes among young adults with type 1 diabetes: A factorial randomized trial (SweetGoals). ↗
- Disease
- Diabetes Mellitus, Type 1
- Substances
- Glycated Hemoglobin · Blood Glucose
- Therapy
- Glycemic Control
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial. ↗
- Disease
- Influenza, Human
- Substances
- Tocotrienols · Influenza Vaccines · Palm Oil
- Therapy
- Vaccination
- Liver Fat Changes in Patients With Type 2 Diabetes by Presence of Genetic Hepatic Steatosis: A Post Hoc Analysis of SURPASS-3 MRI. ↗
- Disease
- Diabetes Mellitus, Type 2 · Fatty Liver
- Substances
- Acyltransferases · Phospholipases A2, Calcium-Independent · Tirzepatide
- Research area
- Survival Outcomes in Cancer Therapy
- Comparative Effectiveness of Pharmacogenomics for Treatment of Depression. ↗
- Substances
- Antidepressive Agents
- Therapy
- Precision Medicine
- Effect of levothyroxine therapy on albuminuria and glomerular function in patients with type 2 diabetes and subclinical Hypothyroidism: a randomized controlled pilot trial. ↗
- Disease
- Diabetes Mellitus, Type 2 · Hypothyroidism · Diabetic Nephropathies
- Substances
- Thyroxine
- Research area
- Heart Failure and Renal Insufficiency Management
- A two-center randomized clinical superiority trial of single-anastomosis sleeve ileal bypass versus sleeve gastrectomy for severe obesity: SASSY study protocol. ↗
- Therapy
- Gastrectomy · Bariatric Surgery
- Research area
- Obesity and Metabolic Disorders
- ADJUNCTIVE MANUKA HONEY ORAL RINSE IN NONSURGICAL PERIODONTAL THERAPY FOR HEMODIALYSIS PATIENTS: A RANDOMIZED CONTROLLED CLINICAL STUDY. ↗
- Disease
- Periodontitis
- Substances
- Fibroblast Growth Factor-23 · Mouthwashes · C-Reactive Protein
- Therapy
- Renal Dialysis
- Silver and Copper Nanoparticles as Non-Antibiotic Therapy for Postpartum Endometritis in Dairy Cows. ↗
- Disease
- Cattle Diseases · Endometritis
- Substances
- Copper · Dinoprost · Glucose
- Effects of Topical Omidenepag Isopropyl on Intraocular Pressure and Pupil Diameter in Normal Dogs. ↗
- Substances
- Ophthalmic Solutions · Glycine · Pyrazoles
- Therapy
- Administration, Topical
- Intensive glycemic control in adults aged 80 years and older: A randomized trial evaluating diabetes complications and competing mortality. ↗
- Disease
- Diabetes Mellitus, Type 2 · Diabetes Complications · Diabetic Angiopathies
- Substances
- Glycated Hemoglobin · Hypoglycemic Agents · Blood Glucose
- Therapy
- Glycemic Control
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Effect of a pharmacist-led mHealth app on adherence, quality of life, and glycaemic control in diabetes: A multicentre RCT. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- Hypoglycemic Agents · Glycated Hemoglobin · Blood Glucose
- Therapy
- Glycemic Control
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Efficacy of co-created, culturally-sensitive intervention for type 2 diabetes self-management education in immigrants in Italy: The DiabEthic randomized clinical trial. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- Glycated Hemoglobin
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Time-Restricted Eating on Appetite and Inflammation in Adults With Obesity and Prediabetes: A Randomized Feeding Study. ↗
- Disease
- Prediabetic State · Diabetes Mellitus, Type 2
- Substances
- Leptin · Ghrelin · Adiponectin
- Research area
- Obesity and Metabolic Disorders
- Oral polychemotherapy to induce remission in newly diagnosed type 2 diabetes: results from a randomized controlled trial. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- Hypoglycemic Agents · Blood Glucose · Glycated Hemoglobin
- Therapy
- Remission Induction · Administration, Oral
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Antimicrobial photodynamic therapy improves wound quality and tissue repair in diabetic foot ulcers: A randomized double blind controlled clinical trial. ↗
- Disease
- Diabetic Foot
- Substances
- Photosensitizing Agents · Methylene Blue · Anti-Infective Agents
- Therapy
- Photochemotherapy
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Hematopoietic Recovery and Safety Following Early Romiplostim Administration After Pediatric HSCT: A Prospective Randomized Pilot Study. ↗
- Disease
- Thrombocytopenia · Hematologic Neoplasms
- Substances
- Thrombopoietin · Recombinant Fusion Proteins · Receptors, Fc
- Therapy
- Hematopoietic Stem Cell Transplantation
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- The effect of foot positioning on tissue oxygenation in diabetic foot ulcers. ↗
- Disease
- Diabetic Foot
- Substances
- Oxygen
- Therapy
- Patient Positioning
- Long-Term Safety and Efficacy of Efgartigimod PH20 in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: ADHERE/ADHERE+ Trial Interim Analysis. ↗
- Substances
- Antibodies, Monoclonal, Humanized
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Within-Day Timing of Concurrent Training Affects Inflammation and Body Composition in Young Adults With Obesity. ↗
- Substances
- Interleukin-6 · Interleukin-10 · Tumor Necrosis Factor-alpha
- Research area
- Obesity and Metabolic Disorders
- A novel oral prodrug (CK301) for effusive feline infectious peritonitis: An open-label study evaluating dose optimization and therapeutic efficacy. ↗
- Disease
- Feline Infectious Peritonitis
- Substances
- Prodrugs · Antiviral Agents · Adenosine
- Therapy
- Administration, Oral
- Effects of Pharmacological GIP Infusion on Insulin, Glucagon, and Cardiovascular Responses During Hyperglycemia in Type 2 Diabetes. ↗
- Disease
- Diabetes Mellitus, Type 2 · Hyperglycemia
- Substances
- Gastric Inhibitory Polypeptide · Insulin · Glucagon
- Therapy
- Infusions, Intravenous
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Effects of Fomepizole on Acetaminophen Oxidative Metabolism: A Randomized, Crossover Study in Human Volunteers. ↗
- Disease
- Drug Overdose · Chemical and Drug Induced Liver Injury
- Substances
- Fomepizole · Acetaminophen · Imines
- Safety, tolerability, relative bioavailability, pharmacokinetics, and pharmacodynamics of single and multiple doses of the novel oral bofanglutide in healthy Chinese participants. ↗
- Substances
- Hypoglycemic Agents · Caprylates · Glucagon-Like Peptide 1
- Therapy
- Administration, Oral
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Pre-exercise meal macronutrient composition and acute inflammatory response in males with type 2 diabetes mellitus. ↗
- Disease
- Diabetes Mellitus, Type 2
- Substances
- C-Reactive Protein · Dietary Fats · Fructose
- Research area
- Obesity and Metabolic Disorders
- Effect of low-dose rivaroxaban plus aspirin on 18F-FDG PET/CT-detectable carotid plaque inflammation: a randomized trial. ↗
- Disease
- Carotid Stenosis
- Substances
- Aspirin · Fluorodeoxyglucose F18 · Rivaroxaban
- Therapy
- Drug Therapy, Combination
- Research area
- Anticoagulation Strategies in Stroke
- Metabolic and vascular outcomes after transition to the MiniMed 780G system in adults ≥65 years with type 1 diabetes: a randomised, single-centre study. ↗
- Disease
- Diabetes Mellitus, Type 1
- Substances
- Insulin · Hypoglycemic Agents · Glycated Hemoglobin
- Therapy
- Insulin Infusion Systems
- Research area
- Diabetes Management and Cardiovascular Outcomes
- Blood Pressure Variability and Outcomes Across Antihypertensive Regimens. ↗
- Disease
- Hypertension · Cardiovascular Diseases
- Substances
- Antihypertensive Agents · Calcium Channel Blockers · Diuretics
- Therapy
- Drug Therapy, Combination
- Research area
- Heart Failure and Renal Insufficiency Management
- Intraosseous Sustained-Release Anesthetics Promote Early Ambulation and Functional Recovery After Total Knee Arthroplasty. ↗
- Substances
- Anesthetics, Local · Delayed-Action Preparations
- Therapy
- Arthroplasty, Replacement, Knee · Delayed-Action Preparations
- Sugammadex versus neostigmine for reversal of neuromuscular blockade and postoperative pulmonary complications (SNaPP): an international, randomised, controlled, phase 4 trial. ↗
- Disease
- Lung Diseases
- Substances
- Sugammadex · Neostigmine · Rocuronium
- Utility of a 40-minute LH level after depot leuprolide for diagnosis and treatment monitoring in girls with CPP. ↗
- Disease
- Puberty, Precocious
- Substances
- Leuprolide · Luteinizing Hormone · Follicle Stimulating Hormone
- Therapy
- Delayed-Action Preparations
- Extending Inferences from a Randomized Trial to Trial-eligible and Treatment-candidate Target Populations: Examples of Generalizability and Transportability. ↗
- Substances
- Hirudins · Heparin · Recombinant Proteins
- Therapy
- Percutaneous Coronary Intervention
- Research area
- Anticoagulation Strategies in Stroke
- Enhanced follicular delivery of minoxidil to human scalp skin using cetosomal formulation. ↗
- Substances
- Minoxidil · Liposomes
- Therapy
- Drug Delivery Systems
- The effects of the PDE4 inhibitor roflumilast on cognitive performance after a cerebrovascular accident: a double-blind randomized placebo-controlled trial with an open label extension (ROSTMEMA). ↗
- Disease
- Stroke · Cognitive Dysfunction
- Substances
- Benzamides · Phosphodiesterase 4 Inhibitors · Cyclopropanes
- Evaluating the impact of cannabinoid extracts on chronic pain and quality of life in endometriosis patients - a pilot study. ↗
- Disease
- Endometriosis
- Substances
- Cannabinoids · Plant Extracts · Analgesics
- Research area
- Psychosocial Impact of Cancer and HIV
- Modified single-stapled anastomosis in laparoscopic or robotic low anterior resection for rectal cancer: protocol for a multicentre randomised controlled trial. ↗
- Disease
- Rectal Neoplasms
- Therapy
- Laparoscopy · Robotic Surgical Procedures
- Research area
- Postoperative Outcomes in Robotic Surgery
- Sirolimus for refractory/relapsed warm autoimmune hemolytic anemia and Evans syndrome: a prospective study. ↗
- Disease
- Anemia, Hemolytic, Autoimmune · Thrombocytopenia
- Substances
- Sirolimus · Immunosuppressive Agents
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Gastric Residual Volume Assessment in Critically Ill Children: The GASTRIC-PICU Randomized Clinical Trial. ↗
- Therapy
- Enteral Nutrition · Respiration, Artificial
- Research area
- Chemotherapy and Immunotherapy in Hematologic Malignancies
- Goal-directed nutritional support in preserving muscle mass and optimising recovery in treatment of oesophageal cancer: results of a prospective non-randomised cluster trial. ↗
- Disease
- Esophageal Neoplasms
- Therapy
- Esophagectomy · Nutritional Support
- Research area
- Survival Outcomes in Cancer Therapy
- Food Effects on the Pharmacokinetics of Single Dose and Steady-State Ralinepag, a Novel Oral Prostacyclin Agonist, in Healthy Volunteers. ↗
- Substances
- Receptors, Epoprostenol · Delayed-Action Preparations · Acetates
- Therapy
- Administration, Oral · Delayed-Action Preparations
No trials match these filters.
Trials are the papers PubMed types as a clinical trial; protocols, which report no results, are left out. PubMed types a paper some time after it appears, so the latest trials may not be listed yet. Past the readouts above, results are not judged here: open a trial on PubMed for its outcome.